Pleomorphic tumours
Pleomorphic tumours have nuclear pleomorphism.
General differential diagnosis
Adapted from Miller with modifications:[1]
| Tumour | Group | Notes |
|---|---|---|
| Melanoma | melanoma | |
| PEComas | mesenchymal lesion | |
| Anaplastic large cell lymphoma | lymphoid | |
| Primary effusion lymphoma | lymphoid | |
| Lymphocyte-depleted Hodgkin lymphoma | lymphoid | |
| Xanthogranuloma | reactive process | |
| Pheochromocytoma | mesenchymal lesion | |
| Choriocarcinoma | carcinoma | |
| Pleomorphic fibroma | mesenchymal lesion | |
| Radiation effect | reactive process | |
| Rhabdomyosarcoma | sarcoma | |
| Leiomyosarcoma | sarcoma | |
| Liposarcoma | sarcoma | |
| Pleomorphic undifferentiated sarcoma | sarcoma | |
| Atypical fibroxanthoma | mesenchymal lesion | |
| Malignant peripheral nerve sheath tumour | sarcoma | |
| Angiosarcoma | sarcoma | |
| Osteosarcoma | sarcoma | |
| Gastrointestinal stromal tumour | sarcoma | |
| Alveolar soft part sarcoma | sarcoma | |
| Malignant solitary fibrous tumour | sarcoma | |
| Inflammatory liposarcoma | sarcoma | |
| Pleomorphic neurothekeoma | mesenchymal lesion | |
| Anaplastic myeloma | lymphoid | |
| Sclerosing extramedullary hematopoetic tumour | lymphoid | rare |
| Smooth muscle tumour of uncertain malignant potential (STUMP) | mesenchymal lesion | rare, may be seen in the prostate gland[2] |
| Inflammatory myxohyaline tumour with Reed-Sternberg like cells | sarcoma | very rare |
| Pleomorphic hyalinizing angiectatic tumour | sarcoma | very rare |
See also
References
- ↑ Miller RT. (Sep 2013). Atlantic Diagnostic Immunohistochemistry Symposium. St. John's, NL, Canada.
- ↑ Nagar, M.; Epstein, JI. (Jun 2011). "Epithelial proliferations in prostatic stromal tumors of uncertain malignant potential (STUMP).". Am J Surg Pathol 35 (6): 898-903. doi:10.1097/PAS.0b013e318214f2f2. PMID 21572264.