Arnault Tzanck
Arnault Tzanck | |
|---|---|
 | |
| Born | May 1, 1886 |
| Died | February 7, 1954 (aged 67) Neuilly-sur-Seine, France |
| Known for | blood transfusion |
| Scientific career | |
| Fields | medicine |
Arnault Tzanck (May 1, 1886 – February 7, 1954) was a French physician and a pioneer of blood transfusion. During the First World War, he was a doctor in the newly-created military motorcar-ambulance service where he realized the vital role of the blood transfusions.[1]
Arnault Tzanck's name is attached to an apparatus he invented that was widely used for transfusing blood in France between the wars, as well as a simple test he devised[2] using the microscopic analysis of scrapings from skin cancer lesions, different ganglia, and some forms of dermatitis especially pemphigus. The Tzanck smear is still widely used as a test for herpes, among other diseases.[3] He also experimented with different methods of preserving blood and blood substitutes. Tzanck's most lasting contribution was in the organization of blood transfusion in France that eventually resulted in the creation of the Centre national de transfusion sanguine, or CNTS (the French National Blood Transfusion Center), which was established in 1949 with Tzanck as its first director. In the process, Tzanck educated a whole generation of serologists and immunologists, including Jean Dausset, Marcel Bessis, and Jean Pierre Soulier.
Modern homage
A deep learning model was developed to analyze Tzanck smears and named after him as TzanckNet.[4]
References
- ^ Schneider, William H (April 2010). "Arnault Tzanck, MD (1886-1954)". Transfus Med Rev. 24 (2). United States: 147–50. doi:10.1016/j.tmrv.2009.11.006. PMID 20303038.
- ^ Tzanck, A. (1947). "Immediate cyto-diagnosis in dermatology". Annales de Dermatologie et de Syphiligraphie. 7 (2): 68. ISSN 0003-3979. PMID 20253311.
- ^ Durdu, Murat (2019). Cutaneous Cytology and Tzanck Smear Test. Springer International Publishing. ISBN 978-3-030-10721-5.
- ^ Noyan, Mehmet Alican; Durdu, Murat; Eskiocak, Ali Haydar (2020-10-27). "TzanckNet: a convolutional neural network to identify cells in the cytology of erosive-vesiculobullous diseases". Scientific Reports. 10 (1): 18314. doi:10.1038/s41598-020-75546-z. ISSN 2045-2322. PMC 7591506. PMID 33110197.
- Cordero, A A (April 1985). "The man behind the eponym. Arnault Tzanck, his work and times". Am J Dermatopathol. 7 (2). United States: 121–3. doi:10.1097/00000372-198504000-00003. ISSN 0193-1091. PMID 3896004.
- Rees, R B (September 1978). "The Tzanck test: a historical vignette". Int. J. Dermatol. 17 (7). United States: 600–1. doi:10.1111/j.1365-4362.1978.tb06008.x. ISSN 0011-9059. PMID 357315. S2CID 21153238.
See also