Jan Poleszczuk

Jan Poleszczuk
Born (1986-10-19) 19 October 1986
Poland
Alma materUniversity of Warsaw (MSc 2010, PhD 2015); Silesian University of Technology (PhD 2014)
Known forMathematical modeling in oncology; modeling of gene expression; optimization of radiotherapy and chemotherapy
Awards
  • POLITYKA Science Award (2017)
Scientific career
FieldsMathematics; Biocybernetics; Biomedical engineering
InstitutionsNałęcz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences; Maria Skłodowska-Curie National Research Institute of Oncology
Thesis Mathematical modeling of cancer cell response to therapy-induced stress (2014); Exploring potential tumor growth modulating mechanisms in cells having different status of TP53 gene (2015)
Doctoral advisorMaria Wideł and Urszula Alicja Foryś
Websitejpoleszczuk.pl

Jan Poleszczuk (born 19 October 1986) is a Polish mathematician and biomedical engineer specializing in mathematical modeling in oncology. He is a researcher at the Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences and a laureate of the Polityka Science Award (2017). His work concerns tumor growth dynamics, gene-expression modeling and optimization of radio- and chemotherapy.

Early life and education

Poleszczuk was born in Poland on 19 October 1986. He received his Master of Science degree in mathematical methods in biology and social sciences from the University of Warsaw in 2010, defending a thesis on modeling tumor angiogenesis and anti-angiogenic therapy based on the Hahnfeldt model.[1]

Under the supervision of Maria Wideł and co-supervision of Urszula Alicja Foryś, he earned a Ph.D. in biocybernetics and biomedical engineering from the Silesian University of Technology in 2014 for the dissertation Mathematical modeling of cancer cell response to therapy-induced stress. He subsequently obtained a Ph.D. in mathematics from the University of Warsaw in 2015 with the thesis Exploring potential tumor growth modulating mechanisms in cells having different status of TP53 gene.

In 2020 he was awarded the habilitation (D.Sc.) in biomedical engineering by the Nałęcz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, for his work Mathematical modeling in the study of evolution and treatment of cancer with radio and immunotherapy.[2]

Academic career

Since 2012 Poleszczuk has been affiliated with the Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences, where he works on quantitative models of tumor response to therapy and radiobiological optimization. He has also collaborated with the Maria Skłodowska-Curie National Research Institute of Oncology on mathematical and computational methods in radiotherapy planning.[3]

Research

Poleszczuk has authored or co-authored more than 60 scientific articles indexed in MathSciNet, Zentralblatt MATH, and PubMed. His most cited works include Stochastic models of gene expression with delayed degradation (co-authored with Jacek Miȩkisz, Marek Bodnar and Urszula Foryś) published in Bulletin of Mathematical Biology (2011) and Mathematical modelling of immune reaction against gliomas: Sensitivity analysis and influence of delays (2013).[4][5]

His research integrates mathematical modeling, systems biology, and biomedical engineering to understand interactions between gene mutations and tumor growth and to improve therapeutic protocols in radiotherapy and chemotherapy.

Awards and membership

References

  1. ^ Foryś, Urszula A. (2012). "Jan Poleszczuk – the Winner of the Polish Mathematical Society's Prize". Mathematica Applicanda. 40: 127–130. doi:10.14708/ma.v40i1.289. ISSN 2299-4009.
  2. ^ "Profil – Ludzie Nauki: dr hab. Jan Poleszczuk". Ludzie Nauki. Retrieved 4 September 2025.
  3. ^ "Jan Poleszczuk – Akademia Młodych Uczonych PAN". Polish Academy of Sciences Academy of Young Scholars. Archived from the original on 24 July 2022. Retrieved 23 January 2025.
  4. ^ Miȩkisz, Jacek; Poleszczuk, Jan; Bodnar, Marek; Foryś, Urszula (2011). "Stochastic Models of Gene Expression with Delayed Degradation". Bulletin of Mathematical Biology. 73 (9): 2231–2247. doi:10.1007/s11538-010-9622-4. PMID 21210242.
  5. ^ Piotrowska, Monika J.; Bodnar, Marek; Poleszczuk, Jan; Foryś, Urszula (2013). "Mathematical modelling of immune reaction against gliomas: Sensitivity analysis and influence of delays". Nonlinear Analysis: Real World Applications. 14 (3): 1601–1620. doi:10.1016/j.nonrwa.2012.10.020. ISSN 1468-1218.
  6. ^ "Laureate of the POLITYKA Scientific Awards 2017". Polityka. Retrieved 20 September 2020.
  7. ^ "Polish Mathematical Society – Main Board 2020". PTM official site. Retrieved 30 December 2020.